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Table 1 Demographic and clinical characteristics within the five categories of platelet counts

From: Lower circulating platelet counts and antiplatelet therapy independently predict better outcomes in patients with head and neck squamous cell carcinoma

 

Platelet count categories

Variable

Low (1-149) N = 67

Low normal (150-229) N = 361

Mid normal (230-314) N = 379

High normal (315-399) N = 169

High (≥400) N = 75

p-value

Age-yrs. Mean (SD)

60.0 (10.7)

61.0 (10.8)

58.4 (11.9)

58.0 (10.8)

58.2 (11.5)

0.009

Male-no. (%)

55 (82)

302 (84)

273 (72)

117 (69)

53 (71)

<0.0001

Race-no. (%)

     

<0.0001

Caucasian

48 (72)

287 (79)

293 (77)

116 (69)

42 (56)

 

African American

18 (27)

67 (19)

83 (22)

52 (31)

33 (44)

 

Other

1 (1.5)

7 (2)

3 (1)

1 (0.5)

0 (0)

 

Smoker-no. (%)

     

<0.0001

Never

6 (9)

63 (19)

67 (19)

18 (11)

4 (6)

 

Former

20 (32)

125 (38)

111 (32)

40 (25)

14 (20)

 

Current

37 (59)

145 (43)

173 (50)

102 (64)

52 (74)

 

Alcohol - no. (%)

     

0.02

Never

17 (27)

99 (30)

108 (29)

36 (23)

7 (10)

 

Former

13 (20)

55 (17)

54 (14)

26 (17)

9 (14)

 

Current

34 (53)

174 (53)

177 (46)

94 (60)

50 (76)

 

Stage

     

0.034

I

6 (11)

42 (15)

42 (14)

8 (7)

5 (8)

 

II

9 (17)

37 (13)

35 (12)

10 (8)

4 (6)

 

III

9 (17)

60 (21)

50 (17)

18 (15)

9 (14)

 

IV

29 (55)

147 (51)

168 (57)

87 (71)

47 (72)

 

Grade

     

0.90

Undetermined

20 (30)

106 (29)

103 (27)

42 (25)

16 (21)

 

I. Well Differentiated

9 (13)

43 (12)

49 (13)

18 (11)

8 (11)

 

II. Moderately

29 (43)

152 (42)

164 (43)

80 (47)

41 (55)

 

III. Poorly or undifferentiated

9 (13)

59 (17)

63 (17)

29 (17)

10 (13)

 

Primary Site

     

0.09

Oral

34 (51)

171 (47)

190 (50)

100 (59)

34 (45)

 

Pharynx

13 (19)

101 (28)

107 (28)

42 (25)

18 (24)

 

Larynx

20 (30)

89 (25)

82 (22)

27 (16)

23 (31)

 

Post-diagnosis NSAIDs and/or Anti-platelets

     

0.33

No no. (%)

48 (72)

259 (72)

277 (73)

133 (79)

60 (80)

 

Yes no. (%)

19 (28)

102 (28)

102 (27)

36 (21)

15 (20)

 
  1. All variables had complete data (n = 1051) except: smoking status (n = 977), alcohol use (n = 953), clinical stage (n = 822) and tumor grade, where the undetermined category accounted for n = 247 cases.