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Table 3 Clinical features of 10 myeloproliferative neoplasm patients with JAK2 Exon 12 mutations

From: The mutation profile of JAK2 and CALR in Chinese Han patients with Philadelphia chromosome-negative myeloproliferative neoplasms

Patient no.

Clinical diagnosis

Age

Gender

JAK2 Exon 12 mutation

WBC (10E9/L)

RBC (10E12/L)

Hb (g/L)

PLT (10E9/L)

J2

PV

44

Male

F537-I546dup10/F547L

14.25

3.94

161

438

J23

PV

60

Male

N533D

9.93

4.45

153

136

J27

PV with splenomegaly

44

Female

F537L

N/A*

J32

PV

43

Male

K539L

7.57

5.83

182

159

J41

PV

35

Male

M532V/E543G

8.33

5.72

180

192

J43

PV with recurrent brain stem hemorrhage

47

Male

D544N

9.11

3.86

112

494

J50

PV

44

Male

E543G

14.46

5.1

166

257

J71

PV

41

Female

N542-E543del

6.46

4.14

143

293

J207

PV

43

Female

H538K539delinsL

5.85

5.81

178

85

J254

PV

23

Female

M535I/H538Y/K539I

7.08

7.46

216

151

  1. *Complete blood count was not available as the patient was in an impaired hematopoiesis condition