Figure 2
From: Cardiac hypertrophy associated with myeloproliferative neoplasms in JAK2V617F transgenic mice
Cardiomegaly in JAK2V617F mice is manifested in increased ventricular wall thickness. The top panel shows representative H&E staining of middle transverse cardiac sections from 40–45 week-old control and JAK2V617F transgenic mice (magnification, ×1.6). Data in the bar graph represents mean ± SD (n ≥10). Note that the left ventricular wall thickness was significantly increased in JAK2V617F transgenic mice (P < 0.01).