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Figure 3 | Journal of Hematology & Oncology

Figure 3

From: Detection of TP53 dysfunction in chronic lymphocytic leukemia by an in vitro functional assay based on TP53 activation by the non-genotoxic drug Nutlin-3: a proposal for clinical application

Figure 3

Functional classification of CLL cases of the training cohort according to both western blot assay and evaluation of CDKN1A induction by qRT-PCR. Histograms show data, obtained by qRT-PCR amplification, of CDKN1A fold increase expression for each CLL case of the training cohort classified according to western blot assay. Arrows indicate CLL cases with a TP53 gene mutated status as evaluated by direct sequencing, asterisks indicate CLL cases with a 17p deletion.

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Journal of Hematology & Oncology

ISSN: 1756-8722

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