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Figure 2 | Journal of Hematology & Oncology

Figure 2

From: High rate of spontaneous inhibitor clearance during the long term observation study of a single cohort of 524 haemophilia A patients not undergoing immunotolerance

Figure 2

The figure shows tests for inhibitors (upper curve) and surgical synovectomy performed at Castelfranco Veneto Haemophilia Centre, 1973–2010. The majority of the tests were performed during the period 1973–1990 when most of the surgical synovectomy programme was developed. The curve shows two peaks, the first during the 70s when the synovectomy programme was more intensive and the second during the mid-80s when patients undergoing synovectomy were overlapped by patients regularly followed up for inhibitor. The last two decades represent the follow up of the patients (right upper curve) and more recent years when surgical synovectomy was completely abandoned and substituted by synoviorthesis (data not reported).

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