From: Epigenetic changes: a common theme in acute myelogenous leukemogenesis
Patent document | Target gene | Method based on |
---|---|---|
WO2006060429 | HDAC1 gene | Detection of five point mutations in HDAC1: M51L, Q111K, T114A, V157G and a premature stop codon at R34 |
WO2012078288 | DNMT3A | Detection of one or more mutations, mainly at Arg-882 |
WO2009150229 | TET2 | Detection of expression levels or mutations in this putative suppressor gene |
US2009317801 | Genes located on the long arm of chromosome 17 (17q25.3) | Analysis of methylation state of a target gene in this chromosomal region |
US2011281270 | CEBPA | Detection of bi allelic mutations in CCAAT-enhancer binding protein gene |