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Table 1 Clinical characteristics of patients with newly diagnosed ENKTL

From: A prospective phase II study of L-asparaginase- CHOP plus radiation in newly diagnosed extranodal NK/T-cell lymphoma, nasal type

Characteristics

Patients

No.

%

Gender

  

  Male

24

63.2%

  Female

14

36.8%

Age, years

  

  >60

2

5.3%

  ≤60

36

94.7%

Ann Arbor Stage

  

  I

20

52.6%

  II

11

28.9%

  III

3

7.9%

  IV

4

10.5%

Subtype of ENKTL

  

  UNKTL

36

94.7%

  EUNKTL

2

5.3%

Tumor extending to adjacent organ/tissue in UNKTL

26 of 36

72.2%

Regional LN involvement

18

47.4%

Bony invasion or perforation

4

10.5%

B symptoms

22 of 38

57.9%

  Fever

18 of 38

47.4%

  Drenching night sweat

9 of 38

23.7%

  Weigh loss

10 of 38

26.3%

ECOG performance status

  

  0

13

34.2%

  1

24

63.2%

  2

1

2.6%

IPI score

  

  0~1

27

71.1%

  2

7

18.4%

  3

2

5.3%

  4~5

2

5.3%

NK/T-cell PI score

  

  0

10

26.3%

  1

13

34.2%

  2

7

18.4%

  3~4

8

21.1%

Serum LDH elevated (>240 IU/L)

7

18.4%

ESR >30 mm/hr

10

26.3%

β2- microglobulin elevated

5

13.2%

Hemoglobin (<110 g/L)

2

5.3%

Leukocytopenia (<4.0 × 109/L)

9

23.7%

  1. Abbreviations: UNKTL Upper aerodigestive tract NK/T- cell lymphoma, EUNKTL Non-upper aerodigestive tract NK/T- cell lymphoma, LN lymph node, ECOG Eastern Cooperative Oncology Group, IPI International prognostic index, NK/T-cell PI NK/T-cell lymphoma prognostic index[27], LDH lactate dehydrogenase, ESR erythrocyte sedimentation rate.