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Figure 5 | Journal of Hematology & Oncology

Figure 5

From: L1cam promotes tumor progression and metastasis and is an independent unfavorable prognostic factor in gastric cancer

Figure 5

L1cam promotes gastric cancer cell growth and metastasis in vivo . (A) SGC7901/Scramble and SGC7901/sh-L1cam cells (1 × 106cells/mouse) were injected subcutaneously into the left and right dorsal flanks of the nude mice (n = 6), tumor volumes were measured on the indicated days. Data points are presented as mean volume ± SD. (B) Histopathology of xenograft tumors, the tumor sections were under HE staining and IHC staining for L1cam and Ki-67. (C) SGC7901/Scramble and SGC7901/sh-L1cam cells (2 × 106cells/mouse) were injected into the tail vein of two groups of nude mice (ten for each group). Six weeks post injection, the mice were killed and the lungs and livers were removed and paraffin embedded.

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