Attributes | MDS | CLL | AML | Control |
|---|
Number | 8 | 4 | 1 | 4 |
Age (year): | 75 (54–90) | 68 (37–84) | 69 (39–85) | 65 (54–79) |
median (range) |
Sex (Male/Female) | 3/5 | 3/1 | 1/0 | 3/1 |
Sample type: | Â | Â | Â | Â |
Peripheral blood | 7 | 3 | 1 | 2 |
Bone marrow | 1 | 1 | 0 | 2 |
Classification (n) | RAEB-1 (n=1) | CLL (n=4) | AMLDN (n=1) | MDS (n=2, RCMD & RAEB-2) |
RAEB-2 (n=2) |
| Â | MDP5q (n=1), | Â | Â | AML (n=1, AML/TDL) |
CLL (n=1) |
RCMD (n=2), |
MDSU (n=1) |
| Â | CMML (n=1) | Â | Â | Â |
- Peripheral white cells were randomly selected from 13 patients carrying the ITPA 94A variant allele and 4 ‘control’ patients homozygous for the ITPA 94C wildtype allele. MDS: Myelodysplastic syndromes; RAEB: Refractory anaemia with excess blasts; RCMD: Refractory cytopenia with multilineage dysplasia; MDP5q: Myelodysplastic syndrome associated with isolated (del)5q chromosomal abnormality; MDSU: Myelodysplastic syndrome unclassifiable; CMML: Chronic myelomonocytic leukaemia; AML: Acute myeloid leukaemia; AML/TLD: Acute myeloid leukaemia with trilineage dysplasia; AMLDN: Acute myeloid leukaemia with multilineage dysplasia without prior myelodysplasia; CLL: Chronic lymphocytic leukaemia.
