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Figure 1 | Journal of Hematology & Oncology

Figure 1

From: Abnormal hematopoietic phenotypes in Pim kinase triple knockout mice

Figure 1

Reduced peripheral platelet counts and erythrocyte hypochromic microcytosis in Pim TKO mice. (A) Peripheral blood white blood cell count and platelet count. (B) Peripheral blood hemoglobin, red blood cell count, MCV and MCH. Peripheral blood samples were collected from 3 different age groups of Pim TKO mice and age-matched WT control mice. Peripheral hematological parameters were measured using Scil ABC plus hematology analyzer (** p < 0.01). Group 1: 1–2 months old (n = 8 for Pim TKO mice); Group 2: 2–4 months old (n = 8 for Pim TKO mice); Group 3: 6–7 months old (n = 3 for Pim TKO mice). (C) Peripheral blood cell subset analysis. Peripheral blood was obtained from 3 months old Pim TKO mice and age-matched WT controls, stained with various antibodies as described in the Materials and Methods, and analyzed by flow cytometry. (*p < 0.05, **p < 0.01).

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