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Table 1 Summary of tumor growth, metastasis, and mice’s survival from three animal experiments of HCCLM3

From: Tanshinone IIA inhibits metastasis after palliative resection of hepatocellular carcinoma and prolongs survival in part via vascular normalization

Items

IE (1)

IE (2)

IE (3)

 

Sham

PR

p

NS

Tan IIA 1

Tan IIA 5

Tan IIA 10

P b

PR+NS

PR+Tan IIA 10

p

TV/cm3

2.712±1.262

5.990±3.113

.014

3.314±0.948

3.643±1.231

3.045±1.031

2.825±0.959

.268

4.736±1.660

3.339±0.924

.047

LM

7.22±4.71

110.11±28.01

.000a

7.42±3.61

6.25±2.77

4.83±3.01

2.25±2.86

.001

94.56±31.47

13.56±11.33

.000

CTCs

0.240±0.082

0.926±0.223

.000

ND

ND

ND

ND

–

0.966±0.276

0.283±0.093

.000a

35 d/%

 

Survival/d

76.833±1.778

51.500±2.784

.000

87.000±3.804

85.500±3.128

96.000±2.658

102.667±3.201

.002

47.833±3.280

69.000±1.693

.001

  1. a Student’s t-test, equal variances assumed.
  2. b One-way analysis of variance.
  3. Abbreviations: PR, palliative resection; NS, normal saline; CTCs, circulating tumor cells; IE, in vivo experiment; LM, lung metastasis; ND, not done; TV, tumor volume.