From: Effect of autoimmune diseases on incidence and survival in subsequent multiple myeloma
0<Age<60 | Age60 | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Autoimmune disease | Pyrs | O | SIR | 95%CI | Deaths | HR | 95%CI | O | SIR | 95%CI | Deaths | HR | 95%CI |
Ankylosing spondylitis | 112824 | 8 | 3.31 | 1.41-6.55 | 3 | 1.00 | 0.32-3.11 | 8 | 1.45 | 0.62-2.87 | 1 | 0.29 | 0.04-2.01 |
Behcet disease | 63182 | 2 | 1.99 | 0.19-7.32 | 0 | 4 | 1.31 | 0.34-3.38 | 3 | 1.05 | 0.34-3.24 | ||
Chronic rheumatic heart disease | 166242 | 6 | 2.79 | 1.00-6.11 | 4 | 1.25 | 0.47-3.33 | 17 | 0.75 | 0.43-1.20 | 5 | 0.82 | 0.34-1.96 |
Crohn disease | 392264 | 5 | 0.89 | 0.28-2.09 | 3 | 1.47 | 0.47-4.57 | 10 | 0.79 | 0.38-1.46 | 6 | 1.12 | 0.50-2.50 |
Graves/hyperthyroidism | 541104 | 7 | 0.98 | 0.39-2.04 | 5 | 2.48 | 1.03-5.98 | 45 | 1.04 | 0.76-1.39 | 24 | 0.80 | 0.53-1.19 |
Hashimoto/hypothyroidism | 120705 | 1 | 0.85 | 0.00 -4.87 | 0 | 14 | 1.17 | 0.64-1.97 | 4 | 0.44 | 0.16-1.16 | ||
Immune thrombocytopenic purpura | 44220 | 0 | 4 | 2.51 | 0.65-6.50 | 2 | 0.57 | 0.14-2.27 | |||||
Multiple sclerosis | 185014 | 3 | 0.86 | 0.16-2.56 | 0 | 10 | 1.04 | 0.49-1.92 | 8 | 1.84 | 0.92-3.68 | ||
Myasthenia gravis | 32648 | 1 | 2.60 | 0.00-14.91 | 1 | 2.41 | 0.34-17.14 | 3 | 1.16 | 0.22-3.45 | 2 | 1.55 | 0.39-6.18 |
Pernicious anemia | 67096 | 1 | 2.38 | 0.00-13.63 | 1 | 0.49 | 3.06-3.48 | 12 | 0.97 | 0.50-1.70 | 11 | 1.30 | 0.72-2.35 |
Polymyalgia rheumatica | 253046 | 5 | 1.93 | 0.61-4.55 | 3 | 0.94 | 0.30-2.92 | 38 | 1.14 | 0.81-1.57 | 24 | 1.05 | 0.70-1.56 |
Polymyositis/dermatomyositis | 24041 | 1 | 3.19 | 0.00-18.26 | 0 | 3 | 1.57 | 0.30-4.65 | 3 | 5.40 | 1.75-16.65 | ||
Psoriasis | 27591 | 5 | 1.19 | 0.38-2.80 | 1 | 0.43 | 0.06-3.06 | 18 | 0.94- | 0.55-1.48 | 10 | 0.80 | 0.43-1.49 |
Rheumatic fever | 77388 | 1 | 0.76 | 0.00-4.35 | 1 | 21.17 | 2.96-151.59 | 7 | 1.50 | 0.60-3.11 | 5 | 4.60 | 1.91-11.06 |
Rheumatoid arthritis | 731954 | 8 | 0.90 | 0.39-1.79 | 2 | 0.45 | 0.11-1.89 | 73 | 0.88 | 0.69-1.10 | 43 | 0.96 | 0.71-1.29 |
Sarcoidosis | 177765 | 4 | 1.26 | 0.33-3.27 | 2 | 1.19 | 0.30-4.78 | 15 | 1.31 | 0.73-2.16 | 9 | 1.07 | 0.55-2.05 |
Sjögren syndrome | 16700 | 1 | 4.58 | 0.00-26.27 | 0 | 3 | 1.78 | 0.33-5.26 | 1 | 0.34 | 0.05-2.38 | ||
Systemic lupus erythematosus | 86627 | 6 | 5.19 | 1.87-11.36 | 3 | 1.42 | 0.46-4.41 | 5 | 0.95 | 0.30-2.23 | 2 | 0.86 | 0.22-3.45 |
Systemic sclerosis | 89997 | 3 | 2.87 | 0.54-8.49 | 3 | 5.51 | 1.75-17.29 | 16 | 2.59 | 1.47-4.2 | 10 | 0.80 | 0.43-1.49 |
Ulcerative colitis | 486704 | 11 | 1.50 | 0.75-2.70 | 6 | 0.85 | 0.38-1.89 | 27 | 1.31 | 0.86-1.90 | 15 | 1.05 | 0.63-1.74 |
Wegener granulomatosis | 115746 | 2 | 3.91 | 0.37-14.36 | 2 | 1.91 | 0.48-7.68 | 24 | 1.11 | 0.71-1.65 | 14 | 0.71 | 0.42-1.20 |
All | 4777665 | 84 | 1.45 | 1.16-1.80 | 40 | 0.96 | 0.70-1.32 | 373 | 1.07 | 0.96-1.18 | 211 | 0.92 | 0.80-1.06 |