From: Effect of autoimmune diseases on incidence and survival in subsequent multiple myeloma
Autoimmune disease (case numbers) | Pyrs | O | SIR | 95%CI | Deaths | HR | 95%CI |
---|---|---|---|---|---|---|---|
Ankylosing spondylitis (6646) | 112824 | 16 | 2.02 | 1.15-3.28 | 4 | 0.60 | 0.22-1.59 |
Behcet disease (3874) | 63182 | 6 | 1.48 | 0.53-3.23 | 3 | 0.64 | 0.21-1.98 |
Chronic rheumatic heart disease (21027) | 166242 | 23 | 0.92 | 0.58-1.39 | 9 | 0.93 | 0.48-1.79 |
Crohn disease (25677) | 392264 | 15 | 0.82 | 0.46-1.36 | 9 | 1.20 | 0.62-2.31 |
Graves/hyperthyroidism (42020) | 541104 | 52 | 1.03 | 0.77-1.35 | 29 | 0.88 | 0.61-1.27 |
Hashimoto/hypothyroidism (13160) | 120705 | 15 | 1.14 | 0.64-1.89 | 4 | 0.40 | 0.15-1.06 |
Immune thrombocytopenic purpura (4324) | 44220 | 4 | 2.13 | 0.55-5.51 | 2 | 0.57 | 0.14-2.30 |
Multiple sclerosis (14616) | 185014 | 13 | 0.99 | 0.53-1.70 | 8 | 1.25 | 0.62-2.49 |
Myasthenia gravis (3044) | 32648 | 4 | 1.35 | 0.35-3.49 | 3 | 1.85 | 0.60-5.74 |
Pernicious anemia (11590) | 67096 | 13 | 1.01 | 0.54-1.74 | 12 | 1.15 | 0.65-2.03 |
Polymyalgia rheumatica (27534) | 253046 | 43 | 1.20 | 0.87-1.62 | 27 | 1.05 | 0.72-1.53 |
Polymyositis/dermatomyositis (2465) | 24041 | 4 | 1.80 | 0.47-4.65 | 3 | 1.41 | 0.45-4.38 |
Psoriasis (19777) | 275971 | 23 | 0.98 | 0.62-1.47 | 11 | 0.75 | 0.41-1.35 |
Rheumatic fever (4306) | 77388 | 8 | 1.34 | 0.57-2.65 | 6 | 5.27 | 2.37-11.75 |
Rheumatoid arthritis (72309) | 731954 | 81 | 0.88 | 0.70-1.09 | 45 | 0.93 | 0.69-1.24 |
Sarcoidosis (11571) | 177765 | 19 | 1.30 | 0.78-2.03 | 11 | 1.05 | 0.58-1.90 |
Sjögren syndrome (1957) | 16700 | 4 | 2.10 | 0.55-5.42 | 1 | 0.30 | 0.04-2.13 |
Systemic lupus erythematosus (7624) | 86627 | 11 | 1.71 | 0.85-3.07 | 5 | 1.10 | 0.46-2.63 |
Systemic sclerosis (7169) | 89997 | 19 | 2.63 | 1.58-4.11 | 13 | 0.92 | 0.53-1.60 |
Ulcerative colitis (33493) | 486704 | 38 | 1.36 | 0.96-1.87 | 21 | 0.96 | 0.62-1.47 |
Wegener granulomatosis (15833) | 115746 | 26 | 1.17 | 0.76-1.72 | 6 | 0.77 | 0.47-1.26 |
All (402462) | 4777665 | 457 | 1.12 | 1.02-1.23 | 251 | 0.92 | 0.81-1.04 |