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Table 1 Patients' characteristics

From: Arsenic trioxide and ascorbic acid interfere with the BCL2 family genes in patients with myelodysplastic syndromes: an ex-vivo study

Characteristics

Patients

 

No.

%

Total patients enrolled

12

Median age, years

69

Sex

  

 Male

7

58

 Female

5

42

IPSS risk score

  

 Low

0

0

 Intermediate 1

7

59

 Intermediate 2

1

8

 High

4

33

WPSS risk score

  

 Very low

1

8

 Low

3

25

 Intermediate

0

0

 High

5

42

 Very high

3

25

WHO classification

  

 RA

3

25

 RARS

0

0

 RCMD

0

0

 RCMD-RS

0

0

 RAEB1

5

42

 RAEB2

4

33

Transfusion dependence at baseline

  

 RBC only

8

67

 PLT only

1

8

 RBC + PLT

1

8

 No

2

17

Cytopenias at baseline

  

 0

0

0

 1

7

58

 2

5

42

 3

0

0

Hematological median values at enrollment

 

 N (x109/L)

2,04

 Hb (g/dL)

8.9

 PLT (x109/L)

174

Karyotype

  

 Normal

5

42

 Complex

2

17

 +8

1

8

 Del7

1

8

Other abnormalities

3

25

  1. RA = refractory anemia, RARS = refractory anemia with ringed sideroblasts, RCMD = refractory cytopenia with multilineage dysplasia, RCMD-RS = refractory cytopenia with multilineage dysplasia and ringed sideroblasts, RAEB-1 = refractory anemia with excess of blasts-1, RAEB-2 = refractory anemia with excess of blasts-2.