Acute graft versus host disease after orthotopic liver transplantation

Table 1 Approaches used in the treatment of acute graft-versus-host disease following orthotopic liver transplantation

Most common treatments	Corticosteroids (most), calcineurin inhibitors (many), granulocyte colony stimulating factors (many)
Antimetabolites	Azathioprine [30]
Alkylating agents	Cyclophosphamide [24]
Anti-T cell antibodies	Anti-thymocyte globulin [5, 19, 24, 31–45]
	OKT3 [24, 42]
	Campath [38, 46, 47]
	Alefacept [43]
Anti-B cell antibodies	Rituximab [46, 48]
Immunoglobulin	Immunoglobulin [4, 49, 50]
Cytokine inhibitors	Infliximab (TNF) [3, 31]
	Etanercept (TNF) [51]
	Daclizumab (IL2R) [3, 38, 41, 46, 52–54]
	Basiliximab (IL2R) [5, 39, 44, 47, 48, 55, 56]
Immunostimulants	Thymosin alpha 1 [4, 41]
Cellular therapy	Ex vivo T cell expansion [47]
	Hematopoietic cell transplantation [24, 32, 34]

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