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Table 4 Fisher’s exact test to evaluate the association between ABCC1 and other clinical factors

From: Detection of ABCC1 expression in classical Hodgkin lymphoma is associated with increased risk of treatment failure using standard chemotherapy protocols

Covariate

Score

ABCC1 Negative

ABCC1 Positive

Fisher's ExactTest (2-Tail)

ABCG2

Negative

39 (79.6%)

10 (20.4%)

.5227

Positive

22 (88%)

3 (12%)

Chemotherapy

ABVD (R-ABVD & MOPP/ABVD)

20 (76.9%)

6 (23.1%)

.8762

CVPP/ABDIC

15 (83.3%)

3 (16.7%)

NOVP

31 (81.6%)

7 (18.4%)

Radiotherapy

No

17 (89.5%)

2 (10.5%)

.3329

Yes

45 (77.6%)

13 (22.4%)

Bone marrow disease

No

62 (79.5%)

16 (20.5%)

1.000

Yes

3 (100%)

0 (0%)

Stage IV disease

No

53 (80.3%)

13 (19.7%)

1.000

Yes

13 (81.3%)

3 (18.8%)

Hemoglobin

≥105 g/l

58 (79.5%)

15 (20.5%)

.6811

< 105 g/l

8 (88.9%)

1 (11.1%)

Albumin

≥ 40 g/l

35 (79.5%)

9 (20.5%)

1.000

< 40 g/l

23 (82.1%)

5 (17.9%)

WBC

<15,000 per mm3

62 (79.5%)

16 (20.5%)

.5814

≥15,000 per mm3

4 (100%)

0 (0%)

Lymphocytes

< 600 per mm3

52 (80%)

13 (20%)

1.000

≥ 600 per mm3

11 (78.6%)

3 (21.4%)

Age ≥45

< 45 years

51 (78.5%)

14 (21.5%)

.5028

≥ 45 years

15 (88.2%)

2 (11.8%)

Sex

Female

26 (76.5%)

8 (23.5%)

.5731

Male

40 (83.3%)

8 (16.7%)

IPS

<3

51 (77.3%)

15 (22.7%)

.2811

 

≥3

14 (93.3%)

1 (6.7%)