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Figure 4 | Journal of Hematology & Oncology

Figure 4

From: The GATA1s isoform is normally down-regulated during terminal haematopoietic differentiation and over-expression leads to failure to repress MYB, CCND2 and SKI during erythroid differentiation of K562 cells

Figure 4

Gene expression changes in GATA1 isoform expressing K562 transgenic cell lines treated with Haemin. Levels of expression of eight target genes (a)-(h) in response to Haemin treatment in GATA1FL- IRESGFP (black bars) and GATA1s- IRESGFP (white bars) transfected K562 cells. Results are expressed as fold change (log2) using day 0 K562 GATA1FL- IRESGFP cells as the calibrator (expression arbitrarily set at 1.0). * p ≤ 0.05, ** p ≤ 0.01 and *** p ≤ 0.001.

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Journal of Hematology & Oncology

ISSN: 1756-8722

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