Table 1 Known targets of protein kinase inhibitors tested
Inhibitors | Known Targets |
|---|---|
Sunitinib | VEGFRs, PDGFRs, KIT, and FLT3 |
Nilotinib | BCR-ABL, KIT, DDRs, PDGFRs, and CSF-1R |
Erlotinib | EGFR and JAK2 |
Gefitinib | EGFR, Her2, and Her3 |
Dasatinib | BCR-ABL, SRCs, and KIT |
Imatinib | BCR-ABL, KIT, and PDGFRs |
Lestaurtinib | FLT3, JAK2, TrkA, TrkB, and TrkC |
Sorafenib | B-Raf, C-Raf, PDGFRs, VEGFRs, KIT, and FLT3 |