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Table 3 Clinical features of Chinese S-ALCL compared with Savage’s report

From: Clinical and laboratory characteristics of systemic anaplastic large cell lymphoma in Chinese patients

Clinical feature ALK+S-ALCL P ALK-S-ALCL P
  This report Savage et al.   This report Savage et al.  
Total no.patients (≥19 years) 23 87   31 72  
Median age, y 38 34   34 58  
Age less than 60 y, no. (%) 22(96) 74(86) 0.175 26(84) 42(58) <0.05
Male–female ratio 2.8:1 1.7:1 0.34 1.8:1 1.5:1 0.68
Stage, no.(%)    0.07    0.53
I 9(40) 1(0)   8(26) 0(0)  
II 4(17) 30(35)   7(23) 30(42)  
III 6(26) 25(29)   10(32) 15(21)  
IV 4(17) 31(36)   6(20) 27(37)  
Nodal-only disease, no. (%) 11(48) 39(54) 0.8 13(42) 38(49) 0.31
Extranodal sites more than 1, no. (%) 4(17) 17(19.5) 0.82 5(16) 15(21) 0.58
Extranodal sites, no. (%)       
Bone marrrow 0 10(12) 0.09 2(5) 5(7) 0.93
Subcutaneous tissue 0(0) 9(10) 0.1 1(3) 2(3) 0.9
Lung 2(8) 7(8) 0.92 1(3) 9(13) 0.14
Bone 3(6) 12(14) 0.93 2(5) 5(7) 0.93
Skin 5(10) 7(8) 0.06 5(16) 12(17) 0.95
Liver 1(4) 3(3) 0.84 2(6) 7(10) 0.59
Spleen 1(4) 9(10) 0.37 4(13) 2(3) <0.05
Pleural effusion 1(4) 3(3) 0.84 2(6) 4(6) 0.86
Pericardial effusiom 0(0) 0(0) 0.6 1(3) 1(1) 0.54
B symptoms, no. (%) 9(39) 52(60) 0.08 11(35) 41(57) <0.05
5-y OS, % 58 70   35 49