Figure 8From: Molecular mechanism of the schedule-dependent synergistic interaction in EGFR-mutant non-small cell lung cancer cell lines treated with paclitaxel and gefitinibSequential modulation of TGFα release and expression. Cells were exposed to IC50 dose of paclitaxel and gefitinib with different sequence. A, standard enzyme-linked immunosorbent assay analysis of soluble TGFα levels in PC-9, Hcc827 and H1650 cells. *p < 0.05, significantly different from control. #P < 0.05, T→G VS G→T. B, reverse transcription-polymerase chain reaction analysis of TGFα expression. *p < 0.05, significantly different from control. #P < 0.05, T→G vs. G→T.Back to article page