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Table 3 IQ in high risk randomisation groups (HDM versus XRT)

From: The impact of therapy for childhood acute lymphoblastic leukaemia on intelligence quotients; results of the risk-stratified randomized central nervous system treatment trial MRC UKALL XI

 

Number of patients

Mean adjusted IQ*

(SD)

Difference in

means

(95% CI)

t-test

p-value

 

HDM

XRT

HDM

XRT

  

FSIQ

      

   3 years

45

51

98.9

(13)

94.7

(13)

4.2

(-1.1 : 9.4)

0.1

   5 years

35

34

100.5

(16)

98.2

(15)

2.3

(-5.1 : 9.8)

0.5

VIQ

      

   3 years

45

51

98.9

(14)

94.9

(13)

4.0

(-1.5 : 9.5)

0.2

   5 years

35

34

100.3

(16)

98.2

(15)

2.0

(-5.5 : 9.6)

0.6

PIQ

      

   3 years

45

51

99.4

(13)

95.7

(13)

3.7

(-1.5 : 8.8)

0.2

   5 years

35

34

101.0

(15)

98.4

(14)

2.7

(-4.3 : 9.7)

0.4

  1. * IQ adjusted for test by subtracting
  2. 7.15 from each WPPSI-R full IQ.
  3. 3.79 from each WPPSI-R verbal IQ.
  4. 8.74 from each WPPSI-R performance IQ.