Figure 5

Neutrophil recovery in neutropenia monkeys administered with G-CSFa and wild-type G-CSF. Neutropenia monkeys were obtained by injection with CTX for 2 days as described in Materials and Methods. Five days after CTX injection, groups of monkey (n = 5) were administered daily via s.c. for 13 days. Peripheral blood absolute neutrophil counts (ANC) were determined at day 5, day 7, day 8, day 10, day 12, day 15, day 17, day 20, day 22, and day 24. The data were summarized from two independent experiments and similar results were obtained.