Signs and Symptoms | |
---|---|
Abdominal | abdominal pain, intestinal cramping and bloating, diarrhea and/or obstipation, nausea, non-cardiac chest pain, Helicobacter pylori-negative gastritis, malabsorption |
Oropharyngeal | burning pain, aphthae |
Respiratory | cough, asthma-like symptoms, dyspnea, rhinitis, sinusitis |
Ophthalmologic | conjunctivitis, difficulty in focusing |
Hepatic | splenomegaly, hyperbilirubinemia, elevation of liver transaminases, hypercholesterolemia |
Splenomegaly | |
Lymphadenopathy | |
Cardiovascular | tachycardia, blood pressure irregularity (hypotension and/or hypertension), syncope, hot flush |
Neuropsychiatric | headache, neuropathic pain, polyneuropathy, decreased attention span, difficulty in concentration, forgetfulness, anxiety, sleeplessness, organic brain syndrome, vertigo, lightheadedness, tinnitus |
Cutaneous | urticaria pigmentosa, hives, efflorescences with/without pruritus, telangiectasia, flushing, angioedema |
Abnormal bleeding | |
Musculoskeletal | muscle pain, osteoporosis/osteopenia, bone pain, migratory arthritis |
Interstitial cystitis | |
Constitutional | fatigue, asthenia, fever, environmental sensitivities |