Figure 3From: Dysregulation of miR-15a and miR-214 in human pancreatic cancerTarget validation of miR-15a and miR-214. (A) The 3'-UTR of WNT3A and FGF7 contain predicted MREs for miR-15a. (B) The 3'-UTR of ING4 contains the predicted MRE for miR-214. (C) A luciferase assay was used to measure the activity of the 3'-UTR reporter in 293T cells. MiR-15a inhibited the activity of WNT3A and FGF7 3'-UTR reporters, whereas miR-214 inhibited the activity of the ING4 3'-UTR reporter.Back to article page