Figure 2From: CD7 in acute myeloid leukemia: correlation with loss of wild-type CEBPA, consequence of epigenetic regulationC/EBPα does not affect CD7 mRNA expression. CEBPA was ectopically expressed in the CEBPA-negative cell line CMY and repressed in the CEBPA-positive cell line NB-4. Expression levels were assessed at day 4 (CEBPA RNAi) and day 13 (ectopic expression of CEBPA) by qRT-PCR. Gene names at the right-hand side of the figure apply for all four columns. Expression of the C/EBPα targets ELA2 and GCSFR depends on CEBPA expression, CD7 mRNA levels are unaffected and remain positive in cell line CMY, negative (neg.) in cell line NB-4.Back to article page