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Figure 5 | Journal of Hematology & Oncology

Figure 5

From: SMI of Bcl-2 TW-37 is active across a spectrum of B-cell tumors irrespective of their proliferative and differentiation status

Figure 5

Effect of TW-37 on the protein expression of Bcl-2, Bcl-X L , Mcl-1, Bax, Bim and β-actin was detected in 4 WSU cell lines, A) WSU-pre-B-ALL, B) WSU-DLCL 2 , C) WSU-FSCCL and D) WSU-WM cell lines after exposure to 250, 500 or 750 nM of TW-37 or its inactive enantiomer TW-37a for 24, 48 or 72 h, cells were harvested, lysed and analyzed by western blot analysis with indicated antibodies.

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