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Figure 3 | Journal of Hematology & Oncology

Figure 3

From: Phenylhexyl isothiocyanate has dual function as histone deacetylase inhibitor and hypomethylating agent and can inhibit myeloma cell growth by targeting critical pathways

Figure 3

PHI inhibits histone deacetylation in RPMI8226 myeloma cells. The RPMI8226 myeloma cells were cultured with two different concentrations of PHI for 72 hours. The proteins were extracted from the cell lysates. The status of histone H3 acetylation was determined by Western blot as described in Material and Methods. β-actin level in the same blot was used as an internal loading control for protein amount.

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